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ENT NEURO

Head & Neck Surgery

CSF Leaks and Dural Repairs - Biodesign is natural extracellular matrix (ECM) derived from porcine small intestinal submucosa (SIS). The ECM is a complex latticework of proteins and structural molecules that help guide the ingrowth of cells. The SIS material is decellularized but preserves the natural matrix molecules such as collagen, proteoglycans, and glycosaminoglycans. The result is an open lattice structure scaffold that, when implanted, provides a location for host cells to infiltrate and remodel into vascularized tissue.

Biodesign Dural and Duraplasty Grafts

Biodesign is a platform technology behind numerous tissue-repair products, spanning multiple specialities.
The Biodesign Dural and Duraplasty Grafts are indicated for use as a dura substitute for the repair of dura mater. The body’s signaling mechanisms help patient cells infiltrate the scaffold and completely remodel into natural host tissue, resulting in a post-op leak rate as low as 1.7%. The Biodesign material is easy to manipulate, doesn’t swell with hydration, and doesn’t fold onto itself. The Biodesign Duraplasty Graft can be secured in place with or without sutures, depending on clinician preference. The grafts are supplied sterile in peel-open packages and are intended for one-time use only.

Otology

Myringoplasty, Tympanoplasty and Mastoidectomy. Biodesign Otologic Repair Grafts are off-the-shelf alternatives to autologous tissue, providing a minimally invasive approach to Tympanic Membrane repair and Mastoid Overlays, with no need to harvest autologous tissue, significantly decreasing intraoperative time and avoiding additional comorbidities and scarring at the donor site. The Biodesign Otologic Repair Graft’s natural extracellular matrix (ECM) is derived from porcine small intestinal submucosa (SIS), completely remodels into natural host tissue, with closure rates ranging from 83%–100% across published literature.

Biodesign Otologic Repair Grafts

The Biodesign Otologic Repair Graft is a 4-layer, Porcine Small Intestinal Submucosa graft, with an overall thickness of .25mm, that enables a truly minimally invasive approach to ear surgery and significantly decreases intraoperative time (average of 7.7 minutes of time savings per procedure). It offers complete closure through neovascularisation and tissue ingrowth. Biodesign is a single use, easy to manipulate graft that does not fold onto itself, allowing for improved surgical precision during graft placement. The convenient sizing options and single use packaging help simplify closures. The circular size options come pre-cut in a case, and the square sheets can be cut to preferred size and shape before placement.

RHINOLOGY

Septoplasty - Nasal Septal Perforation

Biodesign Grafts

COOK Medical’s Biodesign® Grafts are made from Porcine Small Intestineal Submucosa and are easy to handle. The proprietary processing methodology decellularizes the SIS material while preserving natural matrix molecules, such as collagen, proteoglycans, and glycosaminoglycans. The Biodesign material’s natural composition of natural extracellular matrix (ECM) molecules help the body to completely remodel the graft into patient tissue. The result is a scaffold that, when implanted, provides a location for host cells to infiltrate and remodel into vascularized tissue. The 4-layer grafts are available in multiple sizes to meet your specific procedural needs.

Sialendoscopy

Sialendoscopy Product Range (coming soon)